Reduce inflammation, support healthy joints & bones, and keep your skin looking shiny with MSM. MSM 1000 mg from Solgar is a dietary supplement that contains methylsulfonylmethane, an organic sulfur compound and one of the most common substances in our body. It works as a building block for your bones and joints. Plus, MSM provides sulfur which is needed for functions such as protein synthesis, producing energy from fat and carbohydrate.